L-PANTO-D
Composition Pantoprazole 40mg & Domperidone 30mg capsule
Indication Co-Rx with NSAID, GERD, Gastric ulcer
Mechanism of Action

Pantoprazole sodium is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by covalently binding to the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus. The binding to the (H+, K+)-ATPase results in a duration of anti-secretory effect that persists longer than 24 hours for all doses tested

Domperidone: is a peripherally selective dopamine D2 and D3 receptor antagonist. ... The drug provides relief from nausea by blocking receptors at the chemoreceptor trigger zone (a location in the nervous system that mediates nausea) at the floor of the fourth ventricle

Side effects

Abdominal or stomach pain

blurred vision

dry mouth

flushed, dry skin

fruit-like breath odor

Precaution

This medicine may cause hypomagnesemia (low magnesium in the blood). This is more likely to occur if you are taking this medicine for more than one year, or if you are taking this medicine together with digoxin or certain diuretics or "water pills". Check with your doctor right away if you have convulsions (seizures), fast, racing, or uneven heartbeat, muscle spasms (tetany), tremors, or unusual tiredness or weakness.

Dosage

Orally once a day