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LOYFENAC T
Composition Aceclofenac 100 mg, Thiocolchicoside 8/4mg tablet
Indication Acute muscle pain, Acute low back pain, Post-operative pain, Neck and shoulder pain
Mechanism of Action

Thiocolchicoside & Aceclofenac Tablet works by reducesing the swelling and pain; blocking the action of cyclo-oxygenase in the body

Pharmacokinetic's

Absorption- It is rapidly and completely absorbed after oral administration

Distribution- Widely distributed in the body as protein-bound form. It is highly protein-bound (>99.7%). Aceclofenac penetrates into the synovial fluid, where the concentrations reach approximately 60% of those in plasma.

Metabolism- Metabolized into metabolites in the liver. Main metabolite is 4-hydroxyaceclofenac

Excretion- It is excreted through urine mainly as conjugated hydroxymetabolites

Side effects

* Gas

* Allergy

* Diarrhoea

* Urge to vomit

* Brief loss of consciousness

* Sleepiness weakness

* Precautions

Dosage

One tablet twice daily